Mechanics of the Cell
● Lecture plan (separate web-page)
● Course evaluation (exam)
● Evaluation of the course (students opinion)
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Mechanics of the Cell
● Lecture plan (separate web-page)
● Course evaluation (exam)
● Evaluation of the course (students opinion)
|
|
I am in the process of moving to the nano science center and therefore I will not teach this course at KVL again. Lene Oddershede and Kirstine Berg-Sørensen are giving a similar course at NBI starting september 1. 2003: http://www.nbi.dk/~odder/cellmech.html
Time and location
This course will be taught on Wednesdays from September 2002 to December 2002. The lectures start at 9.35 and end at lunch. After lunch there will be tutorials. For about 2 hours.
For the rest of the semester, the lectures and tutorials in "Mechanics of the Cell" have been moved to the Niels Bohr Institute, Blegdamsvej 19, usually room Ma-14 in building M, some times we will have to move to the adjacent auditorium M. The time has not been changed.
The course addresses students with an interest in the mechanical properties and architecture of cells and how these influence cell motion and motion inside the cell. Students who have taken this course will have a thorough understanding of the mechanical properties of the cells components, such as polymers and membranes, and they will understand how these different components work together to form the dynamic properties of the cell.
The course will be given as a joint Master and PhD course, and is aimed at both students with a biological background as well as a background in physics and is offered in collaboration with the Niels Bohr Institute. In order to lay a common ground the course will start with an introduction to different cell types, and the cell’s molecular building blocks as well as an introduction to elementary statistical mechanics and elasticity. The mechanical properties of bio-polymers are then introduced. First the mechanical properties of single polymers then of 2 and 3 dimensional networks of polymers are treated. After this the mechanical properties of membranes are treated. These are combined to understand cell motion and mechanical properties of simple cells. Dynamic filaments such as microtubili, which are important for cell division, are also treated.
The course will closely follow the suggested book by David Boal, but with an emphasis on the biological applications and less emphasis on the mathematical derivations.
In the last decades an increasing understanding of the single processes in a living cell has been obtained. However, in order to understand the whole living cell, it is necessary to combine the single processes to more complex systems. This course offers the students insight in the most recent understanding of one aspect of such complex systems - namely the mechanics of cells.
As course evaluation the students choose one or two research papers of relevance to the course and make a short written report and an oral presentation in an exam.
The course will give 6 ECTS for master students at KVL and KU (physics), probably also for other students but you might have to apply for an approval.
Course responsible: Eva Danielsen, email: eda@kvl.dk , homepage: www.kvl.dk/~eva
Kirstine Berg Sørensen, email: kirstine@nordita.dk ; Homepage: http://www.fys.ku.dk/~kirstine/
If you are a student at KVL, you register the usual way. If you are from outside KVL, then there is some advice at http://www.kvl.dk/main.asp (uddannelse, gæstestuderende) Unfortunately this is only in Danish so far. If that is a problem, please contact me.
On the homepage of KVL it says that you have to register before August 1. I have been informed that the administration is willing to make an exception and take students in from outside KVL after that date.
If you are a PhD student you sign up for the course by contacting me. (Eva Danielsen; eda@kvl.dk )
David Boal: Mechanics of the cell, Cambridge, 2002 (homepage: http://www.sfu.ca/~boal/moc.html )
Available at the bookshop at KVL (ground floor – same building as where the teaching takes place); Price= ?? Dkr
Page 31 In equation 2.11 the power of R should be 4 (also three lines further down)
Page 89 A little below the middle there is a line that ends with “uxy2, “ In that line the second term is divided twice by 2. This should only be once (compare to page 77)
Page 107 Equation 4.13 There should be a curly P in front of the parentheses
Page 108 Equation 4.22 The gammas should be squared
Page 164 equation 5.30 and in figure 5.21, The maximum value of Delta H occurs at a hole radius of lambda/tau (not opposite)
Page 168 about the middle: kA should be kB (Boltzmann’s constant)
Page 225 last paragraph: the reference (Miao et al 1974 should be Miao et al 1994)
Page 242 Is there something wrong in this problem?
Page 285 This problem can not be solved. The area is too small compared to the radius.
